As this trick is an Registry trick i recommend you to Backup your Registry, if you are unaware of how to backup the registry, please click here to learn "How To Backup The Registry"
Thus there is no problem trying this trick on your PC, as i have also shown the trick to enable the USB ports but don't forget to Backup the Registry.
Let's get this job done.
- Click on START and then on RUN.
- Type REGEDIT in the dialogue box and press Enter.
- Now go to the following address, HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\USBSTOR.
- Search for the "START" key in the right side column, and double click on it.
- Change its Value Data from "3" to "4", now its done just close the registry and restart your PC.
- Check that all your USB ports are disabled.
- Now to re-enable the USB port just change the value data from "4" to "3" again
